Detects native and mature IL1 beta. This antibody does not react with Human IL1 alpha. Does not react with Mouse Rat or Rabbit IL2 beta.Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. *   http://www.creative-diagnostics.com/Anti-IL1B-PAb-Biotin-Conjugated-193478-491.htm