Anti-TRAIL Polyclonal Antibody

品牌：solarbio | 货号：K106468P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K106468P-50ul	solarbio	50ul	960.00元
K106468P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-TRAIL Polyclonal Antibody
别名 Apo-2L;APO2L;CD253;TL2;TNLG6A;
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 42kDa
Gene ID 8743
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TRAIL
性状 液体
Public Immunogen Range A synthetic peptide of human TRAIL
Subcellular Locations Cytoplasm
Swiss Prot P50591
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

英文名称	Anti-TRAIL Polyclonal Antibody
别名	Apo-2L;APO2L;CD253;TL2;TNLG6A;
应用	WB
稀释比例	WB 1:3000.
交叉反应	Human Mouse Rat
蛋白分子量	42kDa
Gene ID	8743
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human TRAIL
性状	液体
Public Immunogen Range	A synthetic peptide of human TRAIL
Subcellular Locations	Cytoplasm
Swiss Prot	P50591
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.